Heat Shock Proteins and PD-1/PD-L1 as Potential Therapeutic Targets in Myeloproliferative Neoplasms

Myeloproliferative neoplasms (MPN) are a group of clonal disorders that affect hematopoietic stem/progenitor cells. These disorders are often caused by oncogenic driver mutations associated with persistent Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling. While JA...

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Bibliographic Details
Main Authors: Steven De Almeida, Mathilde Regimbeau, Gaëtan Jego, Carmen Garrido, François Girodon, François Hermetet
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/9/2592