PARP inhibitors in ovarian cancer: evidence, experience and clinical potential

Inhibitors of poly(ADP-ribose) polymerase (PARP) are considered one of the most active and exciting new therapies for the treatment of ovarian cancer. The anticancer activity of PARP inhibitors is based on the DNA repair vulnerability of many ovarian cancer cells, and multiple mechanisms of action o...

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Bibliographic Details
Main Authors: Tarra Evans, Ursula Matulonis
Format: Article
Language:English
Published: SAGE Publishing 2017-04-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758834016687254