Initial evaluation of thyroid dysfunction - Are simultaneous TSH and fT4 tests necessary?

Guidelines for thyroid function evaluation recommend testing TSH first, then assessing fT4 only if TSH is out of the reference range (two-step), but many clinicians initially request both TSH and fT4 (one-step). Given limitations of previous studies, we aimed to compare the two-step with the one-ste...

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Bibliographic Details
Main Authors: Claudio Schneider, Martin Feller, Douglas C Bauer, Tinh-Hai Collet, Bruno R da Costa, Reto Auer, Robin P Peeters, Suzanne J Brown, Alexandra P Bremner, Peter C O'Leary, Peter Feddema, Peter J Leedman, Drahomir Aujesky, John P Walsh, Nicolas Rodondi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5927436?pdf=render