Endogenous retrovirus envelope as a tumor-associated immunotherapeutic target in murine osteosarcoma

Endogenous retrovirus envelope as a tumor-associated immunotherapeutic target in murine osteosarcoma

Summary: Osteosarcoma remains one of the deadliest cancers in pediatrics and young adults. We administered two types of immunotherapies, oncolytic virotherapy and immune checkpoint inhibition, to two murine osteosarcoma models and observed divergent results. Mice bearing F420 showed no response, whe...

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Bibliographic Details
Main Authors: Mary Frances Wedekind, Katherine E. Miller, Chun-Yu Chen, Pin-Yi Wang, Brian J. Hutzen, Mark A. Currier, Brooke Nartker, Ryan D. Roberts, Louis Boon, Joe Conner, Stephanie LaHaye, Benjamin J. Kelly, David Gordon, Peter White, Elaine R. Mardis, Timothy P. Cripe
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:iScience
Subjects:
cancer
immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221007276

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http://www.sciencedirect.com/science/article/pii/S2589004221007276

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