The nephroprotective properties of taurine in colistin-treated mice is mediated through the regulation of mitochondrial function and mitigation of oxidative stress

The nephroprotective properties of taurine in colistin-treated mice is mediated through the regulation of mitochondrial function and mitigation of oxidative stress

Colistin (COL) belongs to the polymixin class of antibiotics used as the last line antibiotic against drug-resistant infections. However, nephrotoxicity is the major deleterious and dose-limiting side effect associated with COL therapy. Oxidative stress and mitochondrial impairment are suspected mec...

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Bibliographic Details
Main Authors: Reza Heidari, Shima Behnamrad, Zahra Khodami, Mohammad Mehdi Ommati, Negar Azarpira, Afsaneh Vazin
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Antibiotics
Mitochondrial impairment
Nephrotoxicity
Oxidative stress
Polymyxin
Taurine
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218364485

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http://www.sciencedirect.com/science/article/pii/S0753332218364485

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