HIV-1 activates macrophages independent of Toll-like receptors.

HIV-1 activates macrophages independent of Toll-like receptors.

Macrophages provide an interface between innate and adaptive immunity and are important long-lived reservoirs for Human Immunodeficiency Virus Type-1 (HIV-1). Multiple genetic networks involved in regulating signal transduction cascades and immune responses in macrophages are coordinately modulated...

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Bibliographic Details
Main Authors: Joseph N Brown, James J Kohler, Carter R Coberley, John W Sleasman, Maureen M Goodenow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2585009?pdf=render

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http://europepmc.org/articles/PMC2585009?pdf=render

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