Next-Generation Sequencing Approaches for the Identification of Pathognomonic Fusion Transcripts in Sarcomas: The Experience of the Italian ACC Sarcoma Working Group

Next-Generation Sequencing Approaches for the Identification of Pathognomonic Fusion Transcripts in Sarcomas: The Experience of the Italian ACC Sarcoma Working Group

This work describes the set-up of a shared platform among the laboratories of the Alleanza Contro il Cancro (ACC) Italian Research Network for the identification of fusion transcripts in sarcomas by using Next Generation Sequencing (NGS). Different NGS approaches, including anchored multiplex PCR an...

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Bibliographic Details
Main Authors: Dominga Racanelli, Monica Brenca, Davide Baldazzi, Frauke Goeman, Beatrice Casini, Biagio De Angelis, Marika Guercio, Giuseppe Maria Milano, Elena Tamborini, Adele Busico, Gianpaolo Dagrada, Cecilia Garofalo, Chiara Caruso, Antonella Brunello, Ymera Pignochino, Enrico Berrino, Giovanni Grignani, Katia Scotlandi, Alessandro Parra, Claudia Maria Hattinger, Toni Ibrahim, Laura Mercatali, Alessandro De Vita, Maria Vincenza Carriero, Matteo Pallocca, Rossella Loria, Renato Covello, Marta Sbaraglia, Angelo Paolo Dei Tos, Rita Falcioni, Roberta Maestro
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Oncology
Subjects:
sarcoma
molecular diagnosis
fusion transcripts
NGS
anchored multiplex PCR
hybrid capture-based panel
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00489/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.00489/full

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