ELK3 Mediated by ZEB1 Facilitates the Growth and Metastasis of Pancreatic Carcinoma by Activating the Wnt/β-Catenin Pathway

Rapid progression and metastasis are the major causes of death in patients with pancreatic ductal adenocarcinoma (PDAC). ELK3, a member of the ternary complex factor (TCF), has been associated with the initiation and progression of various cancers. However, the role of ELK3 in PDAC is not yet fully...

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Bibliographic Details
Main Authors: Qiuyan Zhao, Yingchun Ren, Haoran Xie, Lanting Yu, Jiawei Lu, Weiliang Jiang, Wenqin Xiao, Zhonglin Zhu, Rong Wan, Baiwen Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
EMT
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.700192/full