The unique N-terminal sequence of the BKCa channel α-subunit determines its modulation by β-subunits.

Large conductance voltage- and Ca2+-activated K+ (BKCa) channels are essential regulators of membrane excitability in a wide variety of cells and tissues. An important mechanism of modulation of BKCa channel activity is its association with auxiliary subunits. In smooth muscle cells, the most predom...

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Bibliographic Details
Main Authors: Ramón A Lorca, Xiaofeng Ma, Sarah K England
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5531486?pdf=render