Enhanced intestinal 2-deoxy-2-[18F]fluoro-D-glucose uptake under metformin is not fully suppressed by loperamide

Enhanced intestinal 2-deoxy-2-[18F]fluoro-D-glucose uptake under metformin is not fully suppressed by loperamide

Objective. This study investigated whether the metformin (Met)-induced enhanced intestinal uptake of 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG) is reduced by loperamide, a long-acting anti-diarrheal agent. Methods. Mean 18F-FDG uptake in the mouse small intestine and colon with Met exposure was compa...

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Bibliographic Details
Main Authors: Nobashi Tomomi, Saga Tsuneo, Nakamoto Yuji, Shimizu Yoichi, Koyasu Sho, Ishimori Takayoshi, Watanabe Masao, Kimura Hiroyuki, Togashi Kaori
Format: Article
Language:English
Published: Sciendo 2018-10-01
Series:Endocrine Regulations
Subjects:
18f-fdg
pet/ct
metformin
loperamide
intestine
physiological
Online Access:https://doi.org/10.2478/enr-2018-0023

Internet

https://doi.org/10.2478/enr-2018-0023

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