Doxycycline for Alzheimer’s Disease: Fighting β-Amyloid Oligomers and Neuroinflammation

Alzheimer’s disease (AD) is the most widespread form of dementia, affecting about 45 million people worldwide. Although the β-amyloid peptide (Aβ) remains the most acknowledged culprit of AD, the multiple failures of Aβ-centric therapies call for alternative therapeutic approaches. Conceivably, the...

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Bibliographic Details
Main Authors: Claudia Balducci, Gianluigi Forloni
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00738/full