Phenotypic characterization of Adig null mice suggests roles for adipogenin in the regulation of fat mass accrual and leptin secretion

Phenotypic characterization of Adig null mice suggests roles for adipogenin in the regulation of fat mass accrual and leptin secretion

Summary: Adipogenin (Adig) is an adipocyte-enriched transmembrane protein. Its expression is induced during adipogenesis in rodent cells, and a recent genome-wide association study associated body mass index (BMI)-adjusted leptin levels with the ADIG locus. In order to begin to understand the biolog...

Full description

Bibliographic Details
Main Authors: Anna Alvarez-Guaita, Satish Patel, Koini Lim, Afreen Haider, Liang Dong, Olivia J. Conway, Marcella K.L. Ma, Davide Chiarugi, Vladimir Saudek, Stephen O’Rahilly, David B. Savage
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Cell Reports
Subjects:
adipogenin
adipose tissue
adipogenesis
leptin
knockout mouse
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721001248

Internet

http://www.sciencedirect.com/science/article/pii/S2211124721001248

Similar Items