Muramyl dipeptide promotes Aβ1-42 oligomer production via the NOD2/p-p38 MAPK/BACE1 signaling pathway in the SH-SY5Y cells
The relationship between chronic bacterial colonization in the brain and Alzheimer’s disease is attracting extensive attention. Recent studies indicated that the components of bacterial biofilm drive the amyloid-β production. Muramyl dipeptide, the minimal bioactive peptidoglycan motif common to all...
Main Author: | Yan-Jie Chen, Yuan-Jin Chan, Wen-Jing Chen, Ya-Ming Li, Chun-Yan Zhang |
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Format: | Article |
Language: | English |
Published: |
IMR (Innovative Medical Research) Press Limited
2020-09-01
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Series: | Journal of Integrative Neuroscience |
Subjects: | |
Online Access: | https://jin.imrpress.com/fileup/1757-448X/PDF/1601430238448-990650090.pdf |
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