Synthesis and Enzymatic Incorporation of Modified Deoxyuridine Triphosphates

To expand the chemical functionality of DNAzymes and aptamers, several new modified deoxyuridine triphosphates have been synthesized. An important precursor that enables this aim is 5-aminomethyl dUTP, whereby the pendent amine serves as a handle for further synthetic functionalization. Five functio...

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Bibliographic Details
Main Authors: Erkai Liu, Curtis H. Lam, David M. Perrin
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/8/13591