Scrodentoid A Inhibits Mast Cell–Mediated Allergic Response by Blocking the Lyn–FcεRIβ Interaction

Scrodentoid A Inhibits Mast Cell–Mediated Allergic Response by Blocking the Lyn–FcεRIβ Interaction

Background: Mast cells are considered an attractive therapeutic target for treating allergic diseases, and the Lyn–FcεRIβ interaction is essential for mast cell activation. This study investigated the antiallergic effect of scrodentoid A (SA) on mast cells and mast cell–mediated anaphylaxis.Methods:...

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Bibliographic Details
Main Authors: Fei Qian, Liuqiang Zhang, Shaodong Lu, Gaohui Mao, Fujiang Guo, Ping Liu, Jinwen Xu, Yiming Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
antiallergy
FcεRIβ
Lyn
mast cell
scrodentoid A
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01103/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01103/full

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