Simultaneous determination of minoxidil and minoxidil sulfate by high-performance liquid chromatography with UV-detection and its applications

Aims: Minoxidil is a hair growth drug for treating androgenetic alopecia. Although minoxidil is generally administered as a topical formulation, this prodrug must be converted to its active form (minoxidil sulfate) by sulfotransferase in hair follicle tissue. Therefore, its effect may be affected by...

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Bibliographic Details
Main Authors: Mio Ichida, Chiharu Fujita, Rena Sumie, Ryotaro Miyano, Hajime Inoue
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Medicine in Drug Discovery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590098620300373