Rapid Trio Exome Sequencing for Autosomal Recessive Renal Tubular Dysgenesis in Recurrent Oligohydramnios

Rapid Trio Exome Sequencing for Autosomal Recessive Renal Tubular Dysgenesis in Recurrent Oligohydramnios

Oligohydramnios is not a rare prenatal finding. However, recurrent oligohydramnios is uncommon, and genetic etiology should be taken into consideration. We present two families with recurrent fetal oligohydramnios that did not respond to amnioinfusion. Rapid trio-whole-exome sequencing (WES) reveale...

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Bibliographic Details
Main Authors: Shin-Yu Lin, Gwo-Tsann Chuang, Chien-Hui Hung, Wei-Chou Lin, Yung-Ming Jeng, Ting-An Yen, Karine Chang, Yin-Hsiu Chien, Wuh-Liang Hwu, Chien-Nan Lee, I-Jung Tsai, Ni-Chung Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Genetics
Subjects:
oligohydramnios
AGT gene
autosomal recessive renal tubular dysgenesis
angiotensinogen
whole exome sequencing (WES)
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.606970/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.606970/full

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