Signal regulatory protein alpha negatively regulates beta2 integrin-mediated monocyte adhesion, transendothelial migration and phagocytosis.

Signal regulatory protein alpha negatively regulates beta2 integrin-mediated monocyte adhesion, transendothelial migration and phagocytosis.

BACKGROUND: Signal regulate protein alpha (SIRPalpha) is involved in many functional aspects of monocytes. Here we investigate the role of SIRPalpha in regulating beta(2) integrin-mediated monocyte adhesion, transendothelial migration (TEM) and phagocytosis. METHODOLOGY/PRINCIPAL FINDINGS: THP-1 mon...

Full description

Bibliographic Details
Main Authors: Dan-Qing Liu, Li-Min Li, Ya-Lan Guo, Rui Bai, Chen Wang, Zhen Bian, Chen-Yu Zhang, Ke Zen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2553263?pdf=render

Internet

http://europepmc.org/articles/PMC2553263?pdf=render

Similar Items