Altered glucose homeostasis and hepatic function in obese mice deficient for both kinin receptor genes.

The Kallikrein-Kinin System (KKS) has been implicated in several aspects of metabolism, including the regulation of glucose homeostasis and adiposity. Kinins and des-Arg-kinins are the major effectors of this system and promote their effects by binding to two different receptors, the kinin B2 and B1...

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Main Authors: Carlos C Barros, Anderson Haro, Fernanda J V P Russo, Ines Schadock, Sandro S Almeida, Rosane A Ribeiro, Emerielle C Vanzela, Valeria P Lanzoni, Flavio C Barros, Milton R Moraes, Marcelo A Mori, Reury F P Bacurau, Martin Wurtele, Antônio C Boschero, Everardo M Carneiro, Michael Bader, Joao B Pesquero, Ronaldo C Araujo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3400662?pdf=render