Cytochrome P450 (CYP) and glutathione S-transferases (GST) polymorphisms (CYP1A1, CYP1B1, GSTM1, GSTP1 and GSTT1) and urinary levels of 1-hydroxypyrene in Turkish coke oven workers

Cytochrome P450 (CYP) and glutathione S-transferases (GST) polymorphisms (CYP1A1, CYP1B1, GSTM1, GSTP1 and GSTT1) and urinary levels of 1-hydroxypyrene in Turkish coke oven workers

Genetic polymorphisms of xenobiotic metabolizing enzymes have been associated with cancer risk. We evaluated the influences of genetic polymorphisms of polycyclic aromatic hydrocarbon (PAH) metabolizing enzymes on urinary 1-hydroxypyrene (1-OHP) excretion in Turkish coke oven workers. Urinary 1-OHP...

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Bibliographic Details
Main Authors: Ahmet Oguz Ada, Meltem Yilmazer, Sinan Suzen, Canan Demiroglu, Ali Eba Demirbag, Sibel Efe, Yavuz Alemdar, Sema Burgaz, Mumtaz Iscan
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2007-01-01
Series:Genetics and Molecular Biology
Subjects:
polycyclic aromatic hydrocarbons
1-hydroxypyrene
coke oven workers
cytochrome P450s
glutathione S-transferases
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000400002

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000400002

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