Protein aggregation profile of the human kinome

Protein aggregation into amyloid fibrils is associated with the onset of an increasing number of human disorders, including Alzheimer’s disease, diabetes and some types of cancer. The ability to form toxic amyloids appears to be a property of most polypeptides. Accordingly, it has been proposed that...

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Bibliographic Details
Main Authors: Ricardo eGraña-Montes, Ricardo eSant'anna de Oliveira, Salvador eVentura
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00438/full