The Role of Tricho-Rhino-Phalangeal Syndrome (TRPS) 1 in Apoptosis during Embryonic Development and Tumor Progression

The Role of Tricho-Rhino-Phalangeal Syndrome (TRPS) 1 in Apoptosis during Embryonic Development and Tumor Progression

TRPS1 is a GATA-type transcription factor that is closely related to human tricho-rhino-phalangeal syndrome (TRPS) types I and III, variants of an autosomal dominant skeletal disorder. During embryonic development, Trps1 represses Sox9 expression and regulates Wnt signaling pathways that determine t...

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Bibliographic Details
Main Authors: Aiko Shimokado, Yasuteru Muragaki, Ting Gui, Yujing Sun
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:Cells
Subjects:
Trps1
apoptosis
development
tumorigenesis
Online Access:http://www.mdpi.com/2073-4409/2/3/496

Internet

http://www.mdpi.com/2073-4409/2/3/496

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