Lung resident mesenchymal cells isolated from patients with the Bronchiolitis Obliterans Syndrome display a deregulated epigenetic profile

Abstract Bronchiolitis Obliterans Syndrome is the major determinant of the graft function loss after lung transplantation, but its pathogenesis is still incompletely understood and currently available therapeutic strategies are poorly effective. A deeper understanding of its pathogenic mechanisms is...

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Bibliographic Details
Main Authors: Serena Vella, Pier Giulio Conaldi, Emanuela Cova, Federica Meloni, Rosa Liotta, Salvatore Cuzzocrea, Lavinia Martino, Alessandro Bertani, Angelo Luca, Patrizio Vitulo
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-29504-5