Lack of MOF Decreases Susceptibility to Hypoxia and Promotes Multidrug Resistance in Hepatocellular Carcinoma via HIF-1α

Lack of MOF Decreases Susceptibility to Hypoxia and Promotes Multidrug Resistance in Hepatocellular Carcinoma via HIF-1α

Hypoxia-inducible factor-1α (HIF-1α) promotes oncogenesis in hepatocellular carcinoma and is functionally linked to cell proliferation, chemoresistance, metastasis and angiogenesis. It has been confirmed that the low expression level of Males absent on the first (MOF) in hepatocellular carcinoma lea...

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Bibliographic Details
Main Authors: Meng Wang, Haoyu Liu, Xu Zhang, Wenbo Zhao, Xiaoyan Lin, Fei Zhang, Danyang Li, Chengpeng Xu, Fei Xie, Zhen Wu, Qibing Yang, Xiangzhi Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
MOF
hepatocellular carcinoma
hypoxia inducible factor-1α
hypoxia
protein acetylation
drug resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.718707/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.718707/full

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