Pre-eclampsia is associated with altered expression of the renal sodium transporters NKCC2, NCC and ENaC in urinary extracellular vesicles.

Pre-eclampsia is associated with altered expression of the renal sodium transporters NKCC2, NCC and ENaC in urinary extracellular vesicles.

Pre-eclampsia is a hypertensive disorder of pregnancy characterised by hypertension and sodium retention by the kidneys. To identify changes in sodium uptake proteins in the tubules of the distal nephron, we studied their expression in urinary extracellular vesicles or exosomes (uEVs). Urine was col...

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Bibliographic Details
Main Authors: Chih-Chiang Hu, Marina Katerelos, Suet-Wan Choy, Amy Crossthwaite, Susan P Walker, Gabrielle Pell, Mardiana Lee, Natasha Cook, Peter F Mount, Kathy Paizis, David A Power
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6152984?pdf=render

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http://europepmc.org/articles/PMC6152984?pdf=render

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