The -250G/A and -514C/T Polymorphisms in Hepatic Lipase Gene Promoter Confers an Increased Risk of Hepatocellular Carcinoma in a Chinese Population

Introduction and aim. Hepatocellular carcinoma (HCC) is a lethal malignancy, but the molecular mechanisms of hepatocarcinogenesis remain undefined. The present study aims to investigate the relationship between polymorphisms of the hepatic lipase (HL) gene promoters and risk of HCC.Material and meth...

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Bibliographic Details
Main Authors: Chuan-Zhen Niu, Fu-Hua Zhang, Yan Li, Jing-Jing Liu, Cui-Xia Bao
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119310610