The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide.

The amyloid beta-protein (Abeta) is believed to be the key mediator of Alzheimer's disease (AD) pathology. Abeta is most often characterized as an incidental catabolic byproduct that lacks a normal physiological role. However, Abeta has been shown to be a specific ligand for a number of differe...

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Bibliographic Details
Main Authors: Stephanie J Soscia, James E Kirby, Kevin J Washicosky, Stephanie M Tucker, Martin Ingelsson, Bradley Hyman, Mark A Burton, Lee E Goldstein, Scott Duong, Rudolph E Tanzi, Robert D Moir
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2831066?pdf=render