Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa

Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa

Abstract Background We assessed the utility of a multi-target, real-time PCR assay for Bordetella pertussis detection and diagnosis in patients with severe respiratory illness (SRI), influenza-like illness (ILI), and asymptomatic controls. Methods Real-time PCR detection of IS481, pIS1001, hIS1001 a...

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Bibliographic Details
Main Authors: Fahima Moosa, Mignon du Plessis, Nicole Wolter, Maimuna Carrim, Cheryl Cohen, Claire von Mollendorf, Sibongile Walaza, Stefano Tempia, Halima Dawood, Ebrahim Variava, Anne von Gottberg
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Infectious Diseases
Subjects:
Bordetella pertussis
South Africa
Severe respiratory illness
Influenza-like illness (ILI)
Surveillance
Real-time PCR
Online Access:http://link.springer.com/article/10.1186/s12879-019-3869-7

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http://link.springer.com/article/10.1186/s12879-019-3869-7

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