Identification of RegIV as a novel GLI1 target gene in human pancreatic cancer.

GLI1 is the key transcriptional factor in the Hedgehog signaling pathway in pancreatic cancer. RegIV is associated with regeneration, and cell growth, survival, adhesion and resistance to apoptosis. We aimed to study RegIV expression in pancreatic cancer and its relationship to GLI1.GLI1 and RegIV e...

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Bibliographic Details
Main Authors: Feng Wang, Ling Xu, Chuanyong Guo, Aiwu Ke, Guoyong Hu, Xuanfu Xu, Wenhui Mo, Lijuan Yang, Yinshi Huang, Shanshan He, Xingpeng Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3073946?pdf=render