Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study
The mammalian hyaluronidase degrades hyaluronic acid by the cleavage of the β-1,4-glycosidic bond furnishing a tetrasaccharide molecule as the main product which is a highly angiogenic and potent inducer of inflammatory cytokines. Ursolic acid 1, isolated from Prismatomeris tetrandra, was identified...
Main Authors: | Nor Hayati Abdullah, Noel Francis Thomas, Yasodha Sivasothy, Vannajan Sanghiran Lee, Sook Yee Liew, Ibrahim Ali Noorbatcha, Khalijah Awang |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-02-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/17/2/143 |
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