High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study

High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study

<p>Abstract</p> <p>Background</p> <p>The level of soluble vascular endothelial growth factor receptor 1 (sVEGFR1) is increased in sepsis and strongly associated with disease severity and mortality. Endothelial activation and damage contribute to both sepsis and trauma p...

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Bibliographic Details
Main Authors: Ostrowski Sisse R, Sørensen Anne Marie, Windeløv Nis A, Perner Anders, Welling Karen-Lise, Wanscher Michael, Larsen Claus F, Johansson Pär I
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Subjects:
Trauma
Endothelium
Endothelial cells
Glycocalyx
Soluble vascular growth factor receptor 1
sVEGFR1
sFlt-1
Syndecan-1
Adrenaline
Catecholamines
Sympathoadrenal activation
Online Access:http://www.sjtrem.com/content/20/1/27

Internet

http://www.sjtrem.com/content/20/1/27

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