Bone marrow mesenchymal stem cells derived miRNA-130b enhances epithelial sodium channel by targeting PTEN

Abstract Aims Acute lung injury (ALI) is a clinical syndrome with high morbidity and mortality, and severe pulmonary edema is one of the characteristics. Epithelial sodium channel (ENaC) located on the apical side of alveolar type 2 epithelial (AT2) cells is the primary rate limiting segment in alve...

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Bibliographic Details
Main Authors: Honglei Zhang, Yan Ding, Yapeng Hou, Yanhong Liu, Zhiyu Zhou, Hongguang Nie
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-020-01595-7