Finding melanoma drugs through a probabilistic knowledge graph

Metastatic cutaneous melanoma is an aggressive skin cancer with some progression-slowing treatments but no known cure. The omics data explosion has created many possible drug candidates; however, filtering criteria remain challenging, and systems biology approaches have become fragmented with many d...

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Bibliographic Details
Main Authors: James P. McCusker, Michel Dumontier, Rui Yan, Sylvia He, Jonathan S. Dordick, Deborah L. McGuinness
Format: Article
Language:English
Published: PeerJ Inc. 2017-02-01
Series:PeerJ Computer Science
Subjects:
Online Access:https://peerj.com/articles/cs-106.pdf