Soluble axoplasm enriched from injured CNS axons reveals the early modulation of the actin cytoskeleton.

Axon injury and degeneration is a common consequence of diverse neurological conditions including multiple sclerosis, traumatic brain injury and spinal cord injury. The molecular events underlying axon degeneration are poorly understood. We have developed a novel method to enrich for axoplasm from r...

Full description

Bibliographic Details
Main Authors: Patrick Garland, Lucy J Broom, Shmma Quraishe, Paul D Dalton, Paul Skipp, Tracey A Newman, V Hugh Perry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3480358?pdf=render