Internal Gene Cassette from a Genotype S H9N2 Avian Influenza Virus Attenuates the Pathogenicity of H5 Viruses in Chickens and Mice

Internal Gene Cassette from a Genotype S H9N2 Avian Influenza Virus Attenuates the Pathogenicity of H5 Viruses in Chickens and Mice

H9N2 avian influenza virus (AIV) of genotype S frequently donate internal genes to facilitate the generation of novel reassortants such as H7N9, H10N8, H5N2 and H5N6 AIVs, posing an enormous threat to both human health and poultry industry. However, the pathogenicity and transmission of reassortant...

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Bibliographic Details
Main Authors: Xiaoli Hao, Jiongjiong Wang, Jiao Hu, Xiaolong Lu, Zhao Gao, Dong Liu, Juan Li, Xiaoquan Wang, Min Gu, Zenglei Hu, Xiaowen Liu, Shunlin Hu, Xiulong Xu, Daxin Peng, Xinan Jiao, Xiufan Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Microbiology
Subjects:
avian influenza
H9N2
H5
internal gene cassette
genotype S
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01978/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01978/full

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