Exploring the N-Glycosylation Profile of Glycoprotein B from Human Cytomegalovirus Expressed in CHO and <i>Nicotiana tabacum</i> BY-2 Cells

Exploring the N-Glycosylation Profile of Glycoprotein B from Human Cytomegalovirus Expressed in CHO and <i>Nicotiana tabacum</i> BY-2 Cells

The ability to control the glycosylation pattern of recombinant viral glycoproteins represents a major prerequisite before their use as vaccines. The aim of this study consisted of expressing the large soluble ectodomain of glycoprotein B (gB) from Human Cytomegalovirus (HMCV) in <i>Nicotiana...

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Bibliographic Details
Main Authors: Nicolas Smargiasso, Joseph Nader, Stéphane Rioux, Gabriel Mazzucchelli, Marc Boutry, Edwin De Pauw, François Chaumont, Catherine Navarre
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
glycoprotein B
cytomegalovirus
plant cell suspension culture
N-glycosylation
mass spectrometry
Online Access:https://www.mdpi.com/1422-0067/20/15/3741

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https://www.mdpi.com/1422-0067/20/15/3741

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