BIX01294 suppresses osteoclast differentiation on mouse macrophage-like Raw264.7 cells

BIX01294 suppresses osteoclast differentiation on mouse macrophage-like Raw264.7 cells

Gene expressionis controlled by epigenetic mechanisms including histone methylation. Osteoclasts are bone-resorptive cells that differentiate from hematopoietic-precursor cells by receptor activator of nuclear factor-KB ligand (RANKL) stimulation. Although BIX01294, a specific inhibitor of G9a, whic...

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Bibliographic Details
Main Authors: Hiromasa Tsuda, Ning Zhao, Kenichi Imai, Kuniyasu Ochiai, Pishan Yang, Naoto Suzuki
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2013-11-01
Series:Bosnian Journal of Basic Medical Sciences
Subjects:
osteoclast differentiation
BIX01294
histone methyltransferase
Raw264.7 cell
Online Access:http://bjbms.org/ojs/index.php/bjbms/article/view/2339

Internet

http://bjbms.org/ojs/index.php/bjbms/article/view/2339

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