A novel GIT2-BRAF fusion in pilocytic astrocytoma

Abstract Background KIAA1549-BRAF fusion is the most common genetic event in pilocytic astrocytoma (PA), and leads to activation of the mitogen activated protein kinase (MAPK) signaling pathway. Fusions of BRAF with other partner genes, as well as other genetic alterations not involving BRAF but als...

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Bibliographic Details
Main Authors: Jeffrey Helgager, Hart G. Lidov, Navin R. Mahadevan, Mark W. Kieran, Keith L. Ligon, Sanda Alexandrescu
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Diagnostic Pathology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13000-017-0669-5