Epigenetic Silencing of HOPX Promotes Cancer Progression in Colorectal Cancer

Epigenetic Silencing of HOPX Promotes Cancer Progression in Colorectal Cancer

Homeodomain-only protein X (HOPX)-β promoter methylation was recently shown to be frequent in human cancers and was suggested as tumor suppressor gene in esophageal and gastric cancer. The aim of this study was to investigate the mechanistic roles of HOPX-β promoter methylation and its clinical rel...

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Bibliographic Details
Main Authors: Hiroshi Katoh, Keishi Yamashita, Mina Waraya, Ofer Margalit, Akira Ooki, Hideaki Tamaki, Hiroyuki Sakagami, Kenichi Kokubo, David Sidransky, Masahiko Watanabe
Format: Article
Language:English
Published: Elsevier 2012-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800911

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http://www.sciencedirect.com/science/article/pii/S1476558612800911

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