Immune response to Leishmania (Leishmania) chagasi infection is reduced in malnourished BALB/c mice

Immune response to Leishmania (Leishmania) chagasi infection is reduced in malnourished BALB/c mice

Protein-energy malnutrition and micronutrient deficiencies may down-regulate immune response and increase morbidity and mortality due to infection. In this study, a murine model was used to study the effects of protein, iron and zinc deficiencies on the immune response to Leishmania (Leishmania) cha...

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Bibliographic Details
Main Authors: Tiago Donatelli Serafim, Guilherme Malafaia, Marcelo Eustáquio Silva, Maria Lúcia Pedrosa, Simone Aparecida Rezende
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2010-09-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
visceral leishmaniasis
malnutrition
Leishmania chagasi
BALB/c
interleukin 4
interferon-gamma
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000600014

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000600014

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