G-Protein Inwardly Rectifying Potassium Channel 1 (GIRK1) Knockdown Decreases Beta-Adrenergic, MAP Kinase and Akt Signaling in the MDA-MB-453 Breast Cancer Cell Line

G-Protein Inwardly Rectifying Potassium Channel 1 (GIRK1) Knockdown Decreases Beta-Adrenergic, MAP Kinase and Akt Signaling in the MDA-MB-453 Breast Cancer Cell Line

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Previous data from our laboratory have indicated that there is a functional link between the beta-adrenergic receptor signaling pathway and the G-protein inwardly rectifying potassium channel (GIRK1) in breast cancer cell lines and that these pathways are involved in growth regulation of these cells...

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Bibliographic Details
Main Authors: Michael W. Hance, Madhu S. Dhar, Howard K. Plummer III
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Breast Cancer: Basic and Clinical Research
Subjects:
GIRK
siRNA
breast cancer
real-time PCR
MAP kinase
Akt
beta-adrenergic
Online Access:http://la-press.com/article.php?article_id=651

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http://la-press.com/article.php?article_id=651

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