GRP78 suppresses lipid peroxidation and promotes cellular antioxidant levels in glial cells following hydrogen peroxide exposure.

GRP78 suppresses lipid peroxidation and promotes cellular antioxidant levels in glial cells following hydrogen peroxide exposure.

Oxidative stress, caused by the over production of reactive oxygen species (ROS), has been shown to contribute to cell damage associated with neurotrauma and neurodegenerative diseases. ROS mediates cell damage either through direct oxidation of lipids, proteins and DNA or by acting as signaling mol...

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Bibliographic Details
Main Authors: Kaori Suyama, Masahiko Watanabe, Kou Sakabe, Asako Otomo, Yoshinori Okada, Hayato Terayama, Takeshi Imai, Joji Mochida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3901711?pdf=render

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http://europepmc.org/articles/PMC3901711?pdf=render

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