Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells

<p>Abstract</p> <p>Background</p> <p>Castration resistant prostate cancer (CRPC) develops as a consequence of hormone therapies used to deplete androgens in advanced prostate cancer patients. CRPC cells are able to grow in a low androgen environment and this is associat...

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Bibliographic Details
Main Authors: Shtutman Michael, Tanner Matthew J, Carkner Richard D, Baghel Prateek S, Levina Elina, Feuerstein Michael A, Chen Mengqian, Vacherot Francis, Terry Stéphane, de la Taille Alexandre, Buttyan Ralph
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/89