Functional comparison of induced pluripotent stem cell- and blood-derived GPIIbIIIa deficient platelets.

Functional comparison of induced pluripotent stem cell- and blood-derived GPIIbIIIa deficient platelets.

Human induced pluripotent stem cells (hiPSCs) represent a versatile tool to model genetic diseases and are a potential source for cell transfusion therapies. However, it remains elusive to which extent patient-specific hiPSC-derived cells functionally resemble their native counterparts. Here, we gen...

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Bibliographic Details
Main Authors: Mathias Orban, Alexander Goedel, Jessica Haas, Kirstin Sandrock-Lang, Florian Gärtner, Christian Billy Jung, Barbara Zieger, Elvira Parrotta, Karin Kurnik, Daniel Sinnecker, Gerhard Wanner, Karl-Ludwig Laugwitz, Steffen Massberg, Alessandra Moretti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4301811?pdf=render

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http://europepmc.org/articles/PMC4301811?pdf=render

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