Mas receptor activation attenuates allergic airway inflammation via inhibiting JNK/CCL2-induced macrophage recruitment

Mas receptor activation attenuates allergic airway inflammation via inhibiting JNK/CCL2-induced macrophage recruitment

Background: Defective absorption of acute allergic airway inflammation is involved in the initiation and development of chronic asthma. After allergen exposure, there is a rapid recruitment of macrophages around the airways, which promote acute inflammatory responses. The Ang-(1−7)/Mas receptor axis...

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Bibliographic Details
Main Authors: Luna Hong, Qiujie Wang, Ming Chen, Jianting Shi, Yimin Guo, Shanying Liu, Ruijian Pan, Xiaoqing Yuan, Shanping Jiang
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Mas receptor
Allergic airway inflammation
CCL2
Macrophages
JNK
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221001505

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http://www.sciencedirect.com/science/article/pii/S0753332221001505

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