Differential Redox State Contributes to Sex Disparities in the Response to Influenza Virus Infection in Male and Female Mice

Differential Redox State Contributes to Sex Disparities in the Response to Influenza Virus Infection in Male and Female Mice

Influenza virus replicates intracellularly exploiting several pathways involved in the regulation of host responses. The outcome and the severity of the infection are thus strongly conditioned by multiple host factors, including age, sex, metabolic, and redox conditions of the target cells. Hormones...

Full description

Bibliographic Details
Main Authors: Ignacio Celestino, Paola Checconi, Donatella Amatore, Marta De Angelis, Paolo Coluccio, Rosanna Dattilo, Danilo Alunni Fegatelli, Ann Maria Clemente, Paola Matarrese, Maria Gabriella Torcia, Romina Mancinelli, Caterina Loredana Mammola, Enrico Garaci, Anna Rita Vestri, Walter Malorni, Anna Teresa Palamara, Lucia Nencioni
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
sex differences
gender
hormones
influenza virus
redox state
glutathione
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01747/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01747/full

Similar Items