A solvent-free synthesis of 1-(4-chlorophenyl)pyrazolidin-3-one in a ball mill

An easy, solvent-free method for the synthesis of 1-(4-chlorophenyl)pyrazolidin-3-one has been achieved by grinding 4-chlorophenyl hydrazine and methyl acrylate in the presence of base in a ball mill. A systematic investigation of the reaction has been made in order to study the various factors affe...

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Bibliographic Details
Main Authors: Xiong Zhang, Biao Wang, Binbin Zhang, Yifeng Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Green Chemistry Letters and Reviews
Subjects:
Online Access:http://dx.doi.org/10.1080/17518253.2018.1526332