Investigating the Disordered and Membrane-Active Peptide A-Cage-C Using Conformational Ensembles

Investigating the Disordered and Membrane-Active Peptide A-Cage-C Using Conformational Ensembles

The driving forces and conformational pathways leading to amphitropic protein-membrane binding and in some cases also to protein misfolding and aggregation is the subject of intensive research. In this study, a chimeric polypeptide, A-Cage-C, derived from α-Lactalbumin is investigated with the aim o...

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Bibliographic Details
Main Authors: Olena Dobrovolska, Øyvind Strømland, Ørjan Sele Handegård, Martin Jakubec, Morten L. Govasli, Åge Aleksander Skjevik, Nils Åge Frøystein, Knut Teigen, Øyvind Halskau
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
oligomerizing peptides
bicelles
lipids
conformation
slow exchange
ensemble clustering
Online Access:https://www.mdpi.com/1420-3049/26/12/3607

Internet

https://www.mdpi.com/1420-3049/26/12/3607

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