Improving stability of prediction models based on correlated omics data by using network approaches.

Building prediction models based on complex omics datasets such as transcriptomics, proteomics, metabolomics remains a challenge in bioinformatics and biostatistics. Regularized regression techniques are typically used to deal with the high dimensionality of these datasets. However, due to the prese...

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Bibliographic Details
Main Authors: Renaud Tissier, Jeanine Houwing-Duistermaat, Mar Rodríguez-Girondo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5819809?pdf=render