Virologic failure of protease inhibitor-based second-line antiretroviral therapy without resistance in a large HIV treatment program in South Africa.

We investigated the prevalence of wild-type virus (no major drug resistance) and drug resistance mutations at second-line antiretroviral treatment (ART) failure in a large HIV treatment program in South Africa.HIV-infected patients ≥ 15 years of age who had failed protease inhibitor (PI)-based secon...

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Bibliographic Details
Main Authors: Julie H Levison, Catherine Orrell, Sébastien Gallien, Daniel R Kuritzkes, Naishin Fu, Elena Losina, Kenneth A Freedberg, Robin Wood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3302781?pdf=render